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Category: Today’s Highlights

Amgen: A Revolutionary Migraine Product Might Become the First to Reach the Clinic

MIGRAINE Migraine might have a new potent preventive treatment on the market in the near future. The new breakthrough approach towards migraine treatment aims at targeting and inhibiting calcitonin gene–related peptide (CGPR). Four drug developing firms have ongoing clinical trials...

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May 1, 2017

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Novartis Agreements with Celyad and Bluebird Bio Say a Lot

Novartis signed two different separate licensing agreements with two development-stage firms, Bluebird (BLUE) and Celyad (CYAD) . The signing of the agreements, enabled Novartis to license the two firm’s proprietary technologies, both related to improving Novartis’ genetically engineered immunooncology CAR-...

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May 5, 2017

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Array Biopharma: When Clinical Trial Results Talk

Positive results were announced from Array’s (ARRY) Part 2 of the Phase 3 COLUMBUS study evaluating the firm’s MEK inhibitor drug binimetinib , and its BRAF inhibitor drug encorafenibi n in patients with BRAF-mutant advanced, unresectable or metastatic melanoma. The...

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May 10, 2017

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The Value of Sangamo, Merck and AstraZeneca News

GENE EDITING Sangamo Biosciences: Is it a Comeback? Genome editing allows the creation of therapeutics that can modify the genome in a living cell, providing unprecedented reach that would help the creation of treatments for genetic diseases. The dream about...

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May 15, 2017

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Calming Down PTC Therapeutics Investors' Concerns. More Good News from Sangamo. AERIE's Glaucoma Drug NDA

PTC THERAPEUTICS Why Buying Emflaza? Buying Emflaza, a steroid approved by the FDA for Duchenne muscular dystrophy (DMD) from Marathon Pharmaceuticals invited an intractable headache to PTC Pharmaceuticals’ shareholders and scrutiny by some law makers. The cause of the law...

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May 18, 2017

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Why Amgen's Bone Builder Drug Evenity Will Be Delayed Approval in Spite of Superior Efficacy Results

Amgen’s (AMGN) and UCB's drug Evenity ( romosozumab) , which, in long and large 24 months of clinical investigation has demonstrated superior results in reducing new vertebral, non vertebral and clinical bone fractures, has demonstrated a heart-related side effects. At the weekend...

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May 23, 2017

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Incyte Acquires Ariad Pharmaceuticals European Operations. See Also: A Great Achievement by Illumina

By June, which is next month, Incyte (INCY) will be the owner of the European operations of Ariad (ARIA) . That’s what both firms have announced yesterday. Among other details, the firms decided on signing a licensing agreement for exclusive...

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May 10, 2016

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Giving to Gilead What Belongs to Gilead. Jazz Offers a Needed Relief

GILEAD After years of controversial refraining, official India reversed course and granted Gilead Sciences its patent rights to Sovaldi hepatitis C treatment. More than a victory for Gilead, it was the prevalence of fairness after years of underestimating the power...

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May 11, 2016

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Disrupting the Capability of Cancer Cells to Repair Their Damaged DNA. See Also: Underestimated Biotech Firms

Underestimating the Value of Drugs that Disrupt the DNA Repair Mechanisms in Cancer Cells. AstraZeneca’s (AZN) Chief Executive Pascal Soriot said that while DNA damage response was under-recognized by investors, oncologists were already “very excited” by its potential of the drugs...

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May 16, 2016

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Portola: Solving the Huge Problem of the New Anticoagulants

Notwithstanding the unrelenting improvements being constantly made in managing blood coagulation’s problems, conventional anticoagulants still have thrombotic incidents (clots) in patients taking anticoagulants (blood thinners) and bleeding remained the most feared side effect of these indispensable life-saving drugs. In recent...

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May 18, 2016

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